|
|
Suven Discovery |
 |
|
Research Services Information Letter
June 2010 |
 |
|
Suven Discovery has 8 years experience in discovery and development of several small molecules to clinic in CNS; serving pharma and biotech industry through collaborative research (Eli Lilly) and fee-for-service (AstraZeneca, BMS, Johnson-Johnson, Pfizer, Abbott, Lundbeck, Reviva, Theravance, Onconova, kareus).
Suven Discovery Services: Medicinal Chemistry, Process Chemistry, Analytical Chemistry, Structure-elucidation, Impurities-Metabolite Synthesis; Physicochemical properties;
In-vitro
screening (Receptors-Enzymes); Assay development;
In-vitro and
In-vivo Drug metabolism & Pharmacokinetics in rodents, non-rodents; Brain penetration; Microdialysis; Receptor Occupancy; CNS Pharmacology; Safety Pharmacology;
In-vitro and
In-vivo rodent Toxicology; Histopathalogy; Clinical Pathology, Bioanalysis.
Suven Discovery offers Aggressive timelines together with high scientific quality and documentation for your decision making of molecule progression in drug discovery.
|
|
|
Meet us at the forthcoming events |
| |
|
International
Conference
on Alzheimer’s Disease 2010 (ICAD-2010)
Honolulu, Hawaii
July
10 - 15, 2010
Booth
#
910 |
| |
240th ACS National Meeting & Exposition
Boston, MA
August 22 - 26, 2010
Booth
#
460 |
| |
Society for Neuroscience
Annual Meeting (Neuroscience 2010)
San Diego, CA
November 13 -17, 2010
Booth # 529 |
| |
American
Association of
Pharmaceutical
Scientists (AAPS)
Annual Meeting &
Exposition 2010
New Orleans,
LA
November
15 - 17, 2010
|
| |
|
 |
|
In-vitro
Screening,
Assay
Development & Molecular Biology
|
TOP |
|
Suven Discovery has developed
fully
characterized
and
validated
screening
assays for
targets in GPCR, transporters, Nuclear Receptors and Ligand gated ion
channels.
|
 |
|
Drug Metabolism and Pharmacokinetics
|
TOP |
|
Suven Discovery is dedicated to provide quality PK/TK/ADME services to assist pharmaceutical and biotechnology companies in preclinical development and candidate selection. We have established various
in-vitro (all species, hepatocellular, microsomal, supersomal, plasma, etc) and
in-vivo (Rodent - mice, rat, rabbit, guinea pig & Non Rodent - Beagle dogs) pharmacokinetics and metabolism assays.
|
 |
|
Pharmacology
|
TOP |
|
Suven Discovery has established various safety and
CNS pharmacology (Cognition, Depression
and Pain) models to screen and/or develop lead compounds. We utilize our scientific expertise to validate new drug targets or to develop novel models for assessing client-specific targeting needs.
|
 |
|
Toxicology and Genotoxicity
|
TOP |
|
Suven
Discovery is offering exploratory and discovery rodent (mice and rat) toxicity evaluations (4, 7, 14 and 28 day), including histopathology/review & clinical chemistry and
In-vitro AMES assays to assist pharmaceutical and biotechnology companies in preclinical development and candidate selection.
|
 |
|
Bioanalysis
|
TOP |
|
Suven
Discovery offers a seamless process for your pharmacokinetic and toxicokinetic evaluations, one that begins with formulation and dosing, followed by sample collection and bioanalytical method development, validation and ending with data analysis and report generation. Quantitation of your compound in biological matrices such as blood, plasma, serum, urine, and tissues is usually accomplished using LC-MS/MS. Access to scientific expertise and technical support for data interpretation. All bioanalytical services are conducted according relevant regulatory guidelines.
|
 |
 |
|
 |
 |
|
|
|
Aggressive
Timelines
Together
with High
Scientific
Quality
Decision
Making for
Your NCE’s
Progression
to Clinic |
|
©
2010
Suven Life Sciences
Limited |
|
Serene Chambers, Road -
5, Avenue - 7, Banjara
Hills, Hyderabad-500
034, India |
|
Tel: 91-40-2355 6039 / 2354 1142 / 3311, 3292 1695 / 96, Fax:91-40-2354 1152
E-mail:
jasti@suven.com,
nvsrk@suven.com,
DDDSS@suven.com,
Discovery@suven.com |
|
www.suven.com |
|
|
|